As such patients at extremes of age have low immunity. Additionally patients with diabetes, liver disease, kidney disease also have decreased immunity.
But most important in this group are patients on cancer chemotherapy and patients who have undergone transplant. Infections in this particular group clearly needs expert advice. These patients on chemotherapy and on immunity suppressive therapy can get different rare and multiple infections. There is very little benefit in just starting antibiotics and antifungal without ascertaining the exact nature of problem. Additionally the treatment in such patients can have lot of side effects and needs to be monitored carefully. Options are often limited. Hence such patients who have fever, skin lesion or other infection should seek advice from infectious diseases specialist who have a very good experience in handling such difficult cases.